IP Journal of Urology, Nephrology and Hepatology Science
Official Publication of Khyati Education And Research Foundation
Official Publication of Khyati Education And Research Foundation
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Year 2021
Volume: 4 , Issue: 4
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Original Article
Author Details :
Volume : 4, Issue : 4, Year : 2021
Article Page : 113-115
Abstract
Background: Intra-dialytic hypertension (IDH) pose a great threat in patients on dialysis and proper intervention could prevent its related complications. The aim of this study was to identify the risk factors and drug interventions for IDH.
Methods & Results: Patient attending the nephrology departments of tertiary care hospital were divided in to group A exhibiting intradialytic hypertension on Telmisartan 40 mg BD, group B without intra-dialytic hypertension dialyzed with dialysate Na+ 130mg and group C dialyzed with intensive ultrafiltration for the last three months of the study.
Statistics: Paired sample t- test. Post hoc analysis with one - way anova - Bon Ferroni Results: The results suggest that there were 84 (43.97%) patients undergoing hemodialysis, 74 (38.74%) were having hypertension and (33) 17.27% had IDH. In this study, 12 (6.28%) were patients with IDH out of which 3 (1.57) dies, whereas 2 (1.02) were patients without IDH and none died. Average intra-dialytic rise in BP pre-treatment were 26/12, 26/14 and 28/16 mmHg for group A, B and C respectively. Average intra-dialytic rise in BP post-treatment were 16/10, 18/08 and 12/04 mmHg for group A, B and C respectively. Paired sample ttest. Post hoc analysis with one-way analysis of variance (ANOVA) - Bon Ferroni showed significant value of 0.001 for before treatment - after Telmisartan, 0.002 for before treatment – after low Sodium dialysis and 0.000 for before treatment – after excess fluid removal. In interventions, the mean ± SD was 1.0± 0.023 for Telmisartan/ low sodium intensive ultrafiltration, 1.0±0.02 for low sodium / Telmisartan excess fluid removal and 0.023±0.02 for excess fluid removal / Telmisartan low sodium.
Conclusion: Most effective method to decrease the intra-dialytic hypertension is to increasing the volume of fluid removal during hemodialysis
Keywords: Excess fluid removal, Low Sodium dialysis, Intra-dialytic hypertension, Telmisartan
How to cite : Balakrishnan S, Meenu S, A prospective interventional study on increasing the volume of fluid removal during hemodialysis for patients with Intra-dialytic hypertension (IDH) in a south Indian tertiary care hospital. J Urol Nephrol Hepatol Sci 2021;4(4):113-115
Copyright © 2021 by author(s) and J Urol Nephrol Hepatol Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)
