IP Journal of Urology, Nephrology and Hepatology Science

Current trend in the management of male urethral stricture disease: A review of literature with future directions

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Article Type : Review Article

Author Details: Keyur Parmar,Nikhil Bhachches,Mahesh Chandra*

Volume : 3

Issue : 2

Online ISSN : XXXX

Print ISSN : XXXX

Article First Page : 23

Article End Page : 28

Abstract

Urethral stricture disease is a common urological problem in men with increasing incidence and if left untreated it may result into various life threatening complications. The exact role of CT scan and MRI is yet to be defined. Majority of urologists consider urethroplasty as ‘gold standard’ treatment in the management of urethral stricture. However, to date the excision of diseased urethra and use of graft in urethroplasty has long-term success. The studies evaluating cost factors suggest that either an immediate urethroplasty or a single attempt at internal urethrotomy followed by urethroplasty is cost-effective. Obviously, the trend is toward treatment using reconstructive procedure which cures stricture disease without maintenance procedure e.g. dilation and repeat internal urethrotomy. EPA or augmented urethroplasty using buccal mucosa graft (BMG) are most commonly done procedures. American Urological Association (AUA) symptoms score and uroflometery (UFM) are more useful in the follow up of different urethroplasty. The application of tissue engineering methods has opened a new avenue in the treatment in urethral stricture with stem cells and secretomes awaiting transition from laboratory to clinical use.

Keywords: Urethra, LUTS, UTI, Spongiofibrosis, Stricture, Urethroplasty, Secretomes.

Doi No:-10.18231