IP Journal of Urology, Nephrology and Hepatology Science

Hypogonadotropic Hypogonadism: A review

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Article Type : Review Article

Author Details: Shivam Priyadarshi*,Varsha Kothari,Megha Priyadarshi

Volume : 3

Issue : 2

Online ISSN : XXXX

Print ISSN : XXXX

Article First Page : 34

Article End Page : 37

Abstract

Male hypogonadotropic hypogonadism (HH) is failure of the testes to produce androgens and sperms secondary to congenital or acquired diseases affecting the hypothalamus and/or the pituitary gland. Hypogonadotrophic hypogonadism is suspected if the patient presents with Micropenis with or without cryptorchidism in infancy, delayed or absence of pubertal sexual maturation in adolescents (15-18 yrs age), primary infertility in adults and late onset hypogonadism in aging males. Diagnosis is confirmed by low serum follicle stimulating hormone levels, luteinizing hormone levels and testosterone levels. Imaging (MRI/CT) of brain should be done to rule out pituitary lesions. Treatment requires Androgen replacement therapy till/when fertility is not desired. For fertility Gonadotropins are started to stimulate spermatogenesis. HH is one of the rare conditions in which specific medical treatment can reverse infertility.

Keywords: Hypogonadotropic hypogonadism, Secondary hypogonadism, Male infertility, Subfertility, Azoospermia.

Doi No:-10.18231