As of January 1st, 2022, IP Journal of Urology, Nephrology and Hepatology Science will be ceased publication with IP Innovative Publication. IP Innovative Publication will not publish new content starting from 2022, but will continue to host all published content from 2018-2021, which can be accessed via www.ipinnovative.com/journals/IJUNHS



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Year 2021

Volume: 4 , Issue: 4

IP Journal of Urology, Nephrology and Hepatology Science

Skin and Nail hyperpigmentation (Melanonychia) due to Cyclophosphamide in case of steroid dependant nephrotic syndrome (SDNS): A rare association


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Article Type : Case Report

Author Details: Lakshminarayana GR*,Sahiba E Ummer,Raghunath KV,Muthukumar R

Volume : 3

Issue : 4

Online ISSN : XXXX

Print ISSN : XXXX

Article First Page : 85

Article End Page : 87

Abstract

Cyclophosphamide (CYC) is one the most commonly used second line drug in treatment of nephrotic syndrome, especially in those who are steroid dependant or with frequent relapses. Use of CYC may rarely cause skin or nail hyperpigmentation (melanonychia) apart from other adverse effects related to immunosuppression or cytopenias or hemorrhagic cystitis. We present a patient of steroid dependent nephrotic syndrome (SDNS) who developed blackish brown discoloration of nails and periungual skin folds.

Keywords:  Nephrotic syndrome, Cyclophosphamide, Melanonychia, Hyperpigmentation, Black chromonychia.

Doi No:-10.18231



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