Panacea Journal of Medical Sciences

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To correlate HER-2/neu status in invasive ductal carcinoma breast with histopathological grades of Nottingham score

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Original Article

Author Details : Pooja Agarwal, Dupinder Kaur*

Volume : 11, Issue : 1, Year : 2021

Article Page : 10-12

https://10.18231/j.pjms.2021.003

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Abstract

Background & Methods: The present study entitled “To correlate HER-2/neu status in invasive ductal carcinoma breast with histopathological grades of Nottingham score” was conducted in Dept. of Pathology, at SRMSIMS, Bareilly.
Result: Out of 56 cases all grade 1 tumour were negative for Her2/neu while in grade 2, 17 cases (43.58%) were positive for Her2/neu and in grade 3, 08 cases (80%) were positive for Her 2/neu.
Study Designed: Observational Study
Conclusion: Among all the 60 cases studied it was seen most of the cases with grade 1 tumor were positive for ER & PR receptors & carry better prognosis, while the grade 3 cases were mostly positive for Her2/neu & have poor prognosis. Positive Her2/neu expressed were mostly ER & PR negative & this shows inverse correlation among them.

Keywords: Ductal Carcinoma, Breast, Histopathology & HER-2/neu..

How to cite : Agarwal P , Kaur D , To correlate HER-2/neu status in invasive ductal carcinoma breast with histopathological grades of Nottingham score. Panacea J Med Sci 2021;11(1):10-12

Copyright © 2021 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)