Panacea Journal of Medical Sciences

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Type 2 Diabetes and Inflammation; Correlation of commonly used inflammatory biomarker with marker of glycemic control

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Original Article

Author Details : Anupama Patne, P J Hisalkar, Akanksha Dubey*

Volume : 11, Issue : 1, Year : 2021

Article Page : 13-16

https://10.18231/j.pjms.2021.004

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Abstract

Background: India leads the world with the largest number of Diabetic subjects, hence can be called as Diabetic Capital of World. Diabetes is a serious, chronic disease that occurs due to defects in insulin secretion or insulin action or may be both. Optimal glycemic control is fundamental and still is the main therapeutic objective for the managing and prevention micro and macrovascular complications arising from diabetes that can impact on quality of life. The linkage of inflammation and type 2 diabetes mellitus (T2DM) has been extensively investigated for over a decade. The main objective of the study is to identify
correlation between glycemic control and inflammation.
Materials and Methods: Total 500 subjects were studied which were divided into two groups of 250 of Diabetic cases and Healthy controls after defining proper inclusion and exclusion criteria. Gender wise distribution was also done. HbA1C and CRP were estimated on fully automated analyzers.
Results: The result had shown that cases have significantly elevated HbA1C and CRP when compared to age and sex matched healthy controls with p<0> Conclusion: We can conclude that in developing countries like India estimation of Glycated Hemoglobin and CRP can predict secondary complications of disease.

Keywords: Type 2 Diabetes Mellitus, HbA1C, Glycemic Control, CRP, Inflammation.

How to cite : Patne A , Hisalkar P J, Dubey A , Type 2 Diabetes and Inflammation; Correlation of commonly used inflammatory biomarker with marker of glycemic control. Panacea J Med Sci 2021;11(1):13-16

Copyright © 2021 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)