Panacea Journal of Medical Sciences
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Print ISSN:-2249-8176
Online ISSN:-2348-7682
CODEN : PJMSD7
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Original Article
Author Details :
Volume : 11, Issue : 1, Year : 2021
Article Page : 72-76
https://10.18231/j.pjms.2021.017
Abstract
Background: Scrub typhus is an infectious disease spreads by a bacterium called Orientiatsutsugamushi. The WHO has dubbed scrub typhus one of the world’s most under-diagnosed/underreported diseases. It’s so also in Rajasthan (India). Since antigen detection tests have low sensitivity/specificity and require biopsy specimens, in the clinical setting, serological assays are the mainstay of diagnosis.
Objectives: To study various biochemical parameters in Scrub typhus positive patients and to compare of the same with the control group (negative suspects) to elicit some specific diagnostic parameters through data mining.
Materials and Methods: This retrospective observational cohort study included Fever of unknown origin (FUO) cases classified into patients with (group 1; n = 35) or without (group 2; n= 65) scrub typhus. Various biochemical parameters were correlated and compared through data mining and analyzed on Apache Hive. We used Welch test to estimate normality of data, Fligner Killeen test to estimate the homogeneity of variance and Mann Whitney U test for comparing the two data sets.
Results: Both the groups were comparable with respect to age and sex. Platelet count, SGOT, SGPT and random blood sugar were significantly different in both the groups. (p<0>0.05)
Conclusions: Thrombocytopenia and deranged SGOT-SGPT were found to be prime clinico-pathological indicator of the scrub typhus.
Keywords: Scrub typhus, Data mining, Acute undifferentiated fever, Thrombocytopenia.
How to cite : Jantikar A M, A study of various biochemical parameters in patients with scrub typhus. Panacea J Med Sci 2021;11(1):72-76
Copyright © 2021 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)
