Panacea Journal of Medical Sciences

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Review of clinical presentation of children with celiac disease - A retrospective study

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Original Article

Author Details : Sunil Pathak, Avinash Bothra, Manish Rasania, Dipika Bhil*, Nimya Mary, Prerna Dogra

Volume : 11, Issue : 3, Year : 2021

Article Page : 569-572

https://10.18231/j.pjms.2021.112

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Abstract

Introduction: Celiac disease is a chronic immune mediated enteropathy, produced by the gluten ingestion in susceptible people, where gluten act as environmental trigger. Celiac disease has global prevalence of 1%. Its presentation ranges from simple anaemia, gastrointestinal manifestation, short stature to neurological manifestations. The high level of suspicion helps in prevention of chronic complications of the disease.
Objective: To identify diverse clinical manifestations of children with celiac disease.
Materials and Methods: Children with previously established or newly diagnosed celiac disease, during (2011-2019) were recruited. Data was collected retrospectively from medical records and clinical notes, and subsequently analysed.
Result: The mean age was 7.90 years (3-15 years). 59.09% (13) patients were females. 90.90% (20) patients had gastrointestinal symptoms and anemia and 81.81% (18) had short stature. Other symptoms include lower-limb edema (1), seizure (1), dental caries (1), anasarca (1), abdominal Koch (1), rashes (1), lower limb weakness (1). Biopsy was positive in 7/8 patient.
Conclusion: Knowledge of diverse clinical presentations will help in increased clinician’s awareness and high level of suspicion. It will enable an early diagnosis and management.
 

Keywords: Celiac disease, tTG- tissue transglutaminase, Anemia, short stature

How to cite : Pathak S, Bothra A, Rasania M, Bhil D, Mary N, Dogra P, Review of clinical presentation of children with celiac disease - A retrospective study. Panacea J Med Sci 2021;11(3):569-572

Copyright © 2021 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)