Panacea Journal of Medical Sciences

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Assessment of microbiological profile in peritoneal dialysis in patients with chronic kidney disease

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Original Article

Author Details : M Sornaranjani, CP Ramani*, K Karuppasamy

Volume : 12, Issue : 2, Year : 2022

Article Page : 305-310

https://10.18231/j.pjms.2022.058

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Abstract

Background: Peritonitis is a serious complication of peritoneal dialysis (PD). It is the primary reason for hospitalization and switching over to hemodialysis. In the present study, we aimed to determine the microbiological profile of peritoneal dialysis fluid in patients with acute and chronic renal failure and identify these organisms' susceptibility patterns.
Materials and Methods: This cross-sectional study was conducted in the Institute of Microbiology and Institute of Nephrology in the Rajiv Gandhi Government General Hospital from April 2016 to March 2017. A total of 100 patients who were >18 years of age, acute and chronic renal failure patients who underwent Peritoneal Dialysis and patients on Continuous and Intermittent Peritoneal Dialysis were included.
Results: The study population included 100 patients who satisfied the inclusion criteria. 63% were males, and 37% were females. The patients had a mean age of 44.15±13.89. 28 samples were culture positive, out of which 13 (46.4%) were Gram-negative, 10 (35.7%) were Gram-positive and 5 (17.9%) were Fungal isolates. Among them, the majority were Acinetobacter baumannii (20%) and Candida non-albicans (20%), followed by Staphylococcus aureus (16%), Coagulase-negative Staphylococcus (16%), Klebsiella oxytoca (8%), Klebsiella pneumoniae (4%), Enterococcus faecalis (4%).
Conclusion: Peritoneal infections were more common in patients with longer duration of dialysis and diabetes mellitus. CAPD patients were having a higher risk of infections compared to IPD. As the number of infections associated with peritoneal dialysis rises, routine PD fluid microbiological analysis after the procedure will help improve patient care by using appropriate antibiotics as soon as possible before any major clinical problem arises.
 

Keywords: Peritoneal dialysis, Chronic kidney disease, Culture sensitivity, Hemodialysis, Gram-negative organisms.

How to cite : Sornaranjani M, Ramani C, Karuppasamy K, Assessment of microbiological profile in peritoneal dialysis in patients with chronic kidney disease. Panacea J Med Sci 2022;12(2):305-310

Copyright © 2022 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)