Panacea Journal of Medical Sciences
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Print ISSN:-2249-8176
Online ISSN:-2348-7682
CODEN : PJMSD7
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Year 2024
Volume: 14 , Issue: 2
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Original Article
Author Details :
Volume : 12, Issue : 2, Year : 2022
Article Page : 330-334
https://10.18231/j.pjms.2022.062
Abstract
Background: Leucoerythroblastosis was considered as a circulating expression of haematological and non-haematological malignancies. However many benign conditions are also associated with leucoerythroblastosis such as hemolytic anaemia, marked infections and congestive cardiac failure, etc. So the study was performed to determine the various causes of leucoerythroblastic blood picture on bone marrow examination.
Materials and Methods: The current retrospective diagnostic analytical study was performed in the hematology section of post graduate department of pathology over a period of one year. 80 patients with leucoerythroblastic picture on peripheral blood film (PBF), who were subjected to bone marrow aspiration and/or biopsy were included in the study. The findings were documented on a predefined performa and results tabulated.
Majority of cases were seen in 21-30 years age group (25%) with male to female ratio of 1.1:1. Non-neoplastic disorders accounted for majority of cases (65%) while neoplastic lesions were seen in 35% cases. Megaloblastic anaemia was the commonest neo-neoplastic etiology while acute leukemia was the commonest neoplastic disorder in the present study.
Conclusions: Leucoerythroblastosis represents disordered marrow function and is reflected in PBF. Bone marrow aspiration and biopsy help in establishing early diagnosis and management of the underlying condition.
Keywords: Leucoerythroblastosis, Trephine, Myelofibrosis
How to cite : Sharma P, Hans D, Naz N, Role of bone marrow aspiration and biopsy in evaluation of leucoerythroblastic blood picture. Panacea J Med Sci 2022;12(2):330-334
Copyright © 2022 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)
