Panacea Journal of Medical Sciences

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Cutaneous adverse drug reactions in geriatric patients in Odisha

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Original Article

Author Details : Satyabrata Sahoo*, Suhasini Dehury, Sabita Mohapatra, Namita Mohapatra, Prasanjit Mohanty

Volume : 12, Issue : 3, Year : 2022

Article Page : 493-496

https://10.18231/j.pjms.2022.093

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Abstract

Background & Objective: Geriatrics is a speciality that focuses on healthcare of elderly people. Geriatric population is defined as people above 60 years of age. Geriatric population constitute 8.14% of total population in India. They have diverse physiological and pathological profiles which have an impact on the pharmacokinetic & pharmacodynamic properties of the administered drug. Very often they are under polypharmacy due to multisystem involvement and thereby subjected to numerous drug interactions and adverse drug reactions. There are few studies conducted in India regarding adverse drug reactions (ADRs) in Geriatric Patients and none in Odisha. Hence this study aims to evaluate the cutaneous ADRs encountered in geriatric patients.
Materials and Methods: This hospital based observational study was conducted in Dept of Pharmacology in collaboration with Medicine and Skin &VD of SCB Medical College & Hospital. All geriatric patients (aged ? 60 yrs) diagnosed with ADR, from August 2017 to July 2018, were included. The detailed information of type of ADR and its characteristics were filled up in Suspected Adverse Drug Reaction Reporting Form. The prevalence and profile of Cutaneous ADRs were studied. Their causality, severity and preventability were assessed by WHO-UMC System, Hartwig’s Severity Scale and Schumock Thornton Preventability Scale respectively.
Result: A total of 102 geriatric ADRs were reported in 1 year, out of which 47% were Cutaneous ADRs. Out of the Cutaneous ADRs 73 % ADRs were probable, 62.5 % were Moderate in intensity and 58.3% of were definitely preventable. Rash (27%) was the most common cutaneous ADR detected.
Conclusion: Most of the ADRs were probably caused due to the drug, were moderate in intensity and definitely preventable.
 
Keywords: ADR, Geriatric Population, Odisha, GI, CNS

How to cite : Sahoo S, Dehury S, Mohapatra S, Mohapatra N, Mohanty P, Cutaneous adverse drug reactions in geriatric patients in Odisha. Panacea J Med Sci 2022;12(3):493-496

Copyright © 2022 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)