Panacea Journal of Medical Sciences
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Print ISSN:-2249-8176
Online ISSN:-2348-7682
CODEN : PJMSD7
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Year 2024
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Original Article
Author Details :
Volume : 12, Issue : 3, Year : 2022
Article Page : 634-640
https://10.18231/j.pjms.2022.118
Abstract
Background: Chronic kidney disease (CKD) is defined as the presence of kidney damage. Hypothyroidism is prevalent in patients with CKD, including those on dialysis.
Materials and Methods: The present observational cross-sectional study included 120 patients (70 subjects and 50 controls) who had previously been diagnosed with chronic kidney disease and primary hypothyroidism, as well as those who presented with primary hypothyroidism alone. Serological Estimation of Anti-TPO Antibody, T3, T4 and TSH levels were done as per standard protocol.
Results: We enrolled 120 patients, 70 of whom had hypothyroidism in addition to CKD and 50 of whom had hypothyroidism without CKD. Twenty percent of the cases tested positive for anti-TPO antibodies, while 80 % tested negative for anti-TPO antibodies. 71.5 % of positive cases were female, while 28.5 % were male. Among the controls, 74% were positive for anti-TPO antibodies, and 26% were negative. 64.9 % of the positive controls were female, while 35.1 % were male.
Conclusion: Our findings indicate that primary hypothyroidism is prevalent in a subgroup of patients with chronic kidney disease. The non-autoimmune mechanism appears to be more prevalent. However, additional multi-centric studies will be necessary to improve the reliability and generalizability of the current study's observations.
Keywords: Chronic kidney disease, Hypothyroidism, Thyroid Autoimmune Antibody
How to cite : Mishra C, Sarkari M, Mishra S, To study the prevalence of thyroid autoimmune antibody in chronic kidney disease patients with hypothyroidism in Eastern Uttar Pradesh. Panacea J Med Sci 2022;12(3):634-640
Copyright © 2022 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)
