Panacea Journal of Medical Sciences

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An observational study to compare the effect of intravenous dexmedetomidine versus intravenous magnesium sulphate pretreatment on characteristics of spinal anaesthesia

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Original Article

Author Details : Akash Gajendra, Tripti Vatsalya, Vikas Gupta, Vandana Pandey*, Shikha Mehrotra

Volume : 13, Issue : 1, Year : 2023

Article Page : 25-31

https://10.18231/j.pjms.2023.006

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Abstract

Background and Aims: The study was conducted to assess & compare the effect of pretreatment with intravenous Dexmedetomidine and Magnesium sulphate on characteristics of SAB with hyperbaric bupivacaine.
Materials and Methods: 80 ASA grade I and II patients (age: 18-60 years) scheduled for infraumblical surgery under spinal anesthesia were included & randomly divided into group-D (dexmedetomidine 1? gm/kg) and group-M (magnesium sulfate 50 mg/kg). patients were given prefixed doses of either intravenous dexmedetomidine or Magnesium sulfate 15 mins before SAB. Incidence of hypotension, highest level & duration of sensory & motor blockage, duration of analgesia, vasopressor requirement and incidence of sedation, nausea & vomiting were compared.
Results: Highest upper level of sensory block after SAB was higher in group-D (p value < 0> Conclusion: Study suggests that Intravenous dexmedetomidine at a dose of 1?g/kg is a better adjuvant to 0.5% hyperbaric bupivacaine than MgSo at a dose of 50 mg/kg in infra-umbilical surgeries, with complications of hypotension and bradycardia occurring at acceptable incidences.

Keywords: Intravenous dexmedetomidine, Magnesium sulphate, Subarachnoid block (SAB), Adjuvents, analgesia, Infraumblical surgery

How to cite : Gajendra A, Vatsalya T, Gupta V, Pandey V, Mehrotra S, An observational study to compare the effect of intravenous dexmedetomidine versus intravenous magnesium sulphate pretreatment on characteristics of spinal anaesthesia. Panacea J Med Sci 2023;13(1):25-31

Copyright © 2023 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)