Panacea Journal of Medical Sciences

---

Study of altered blood glucose levels in term neonate with sepsis

Full Text PDF Share on Facebook Share on Twitter

---

Original Article

Author Details : Subhakankshi Barik, Madhusmita Pradhan, Jyotiranjan Champatiray, Mangal Charan Murmu*

Volume : 13, Issue : 2, Year : 2023

Article Page : 289-294

https://10.18231/j.pjms.2023.056

Suggest article by email

---

Abstract

Introduction: Neonatal hypoglycemia is common metabolic disorder. Hyperglycemia can also occur in other conditions like exogenous parenteral glucose administration, preterm, ELBW babies, stressed premature infants (requiring mechanical ventilation), hypoxia or neonatal diabetes mellitus. The major clinical problems associated with hyperglycemia are hyper osmolality and osmotic dieresis leading to alteration in cerebral auto regulation. Aim & objective: To study the effect of hyperglycemia in term neonate with sepsis and compare it with hypoglycemia.
Materials and Methods: It is a hospital based prospective observational study .The study was carried out in the special care neonatal unit and pediatric indoor of Department of Pediatrics, SCB Medical College, Cuttack and SVP Postgraduate Institute of Pediatrics, Cuttack during the period from September 2018 to August 2020.
Observation: The number of cases of neonatal sepsis with normoglycemia hypoglycemia and hyperglycemia were, 90(44%), 67(32%), 52(24%) cases respectively. The total number of cases with proven sepsis (n=47) hyperglycemia accounts for 40.4%of cases followed by hypoglycemia 18 cases (38.3%) and normoglycemia seen in 10 cases (21.2%).
Conclusion: Both hypoglycemia and hyperglycemia were associated with increased mortality rates at all thresholds but hyperglycemia was independently associated with increased odds of death in patients with neonatal sepsis compared to hypoglycemia.
 
Keywords: Blood Glucose, Neonate, Sepsis, Hypoglycemia, Hyperglycemia

How to cite : Barik S, Pradhan M, Champatiray J, Murmu M C, Study of altered blood glucose levels in term neonate with sepsis. Panacea J Med Sci 2023;13(2):289-294

Copyright © 2023 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)