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Panacea Journal of Medical Sciences


Follow up of serum ferritin levels in myocardial infarction in Indian males


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Original Article

Author Details : Shikha Agarwal*, Praveen Sablania

Volume : 13, Issue : 3, Year : 2023

Article Page : 602-605

https://10.18231/j.pjms.2023.111

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Abstract

Introduction: National health & nutritional examination survey, 1988-1994, first time reported a significant positive association in iron storage & heart disease risk. Due to the scarcity of this type of study in India, we did this study to find out the relation of serum ferritin with MI
Aim: The current study attempts to evaluation association of ferritin levels at the onset of AMI & at 6 day of follow up of subjects.
Materials and Methods: A total of 39 male patients who were confirmed of having MI on the basis of lipid profile, CKMB, SGOT, SGPT, Trop I, ECG & Chest X Ray were included in the study. Serum ferritin level was estimated in study group on day 1 & day 6 of MI attack while only once in control. Serum ferritin was estimated by enzyme linked fluorescent assay on Mini Vidas auto analyzer from Biomerieux.
Results: Mean serum ferritin levels at Day-1 was not significantly elevated than controls [58.51 (±18.71) ng/ml in day-1 versus 64.09 (±19.42)]. In contrast serum ferritin levels at Day-6 were significantly elevated than controls [226.68 (±18.71) ng/ml at day-6 versus versus ferritin levels in controls (p < 0> Conclusion: In conclusion, our data supports that elevated serum ferritin levels are associated with pathogenesis of AMI.
 

Keywords: Ferritin, Myocardial infarction, AMI, iron, Inflammation, Oxidative stress, Lipid peroxidation, Ferroptosis


How to cite : Agarwal S, Sablania P, Follow up of serum ferritin levels in myocardial infarction in Indian males. Panacea J Med Sci 2023;13(3):602-605

Copyright © 2023 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)