Panacea Journal of Medical Sciences

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An observational study to determine relationship of serum hydrogen sulphide level in hypothyroid patients in a medical college in Kolkata

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Original Article

Author Details : Ankita Bhattacharya, Sadajit Banerjee, Ipsita Bhattacharyya, Pinaki Saha*, Debmalya Sanyal, Indira Bhaskar Biswas

Volume : 13, Issue : 3, Year : 2023

Article Page : 824-828

https://10.18231/j.pjms.2023.150

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Abstract

Hypothyroidism is an endocrinopathy eventuate due to destruction of thyroid cells incapacitating synthesis of thyroid hormones. HS which is a gas signaling molecule that might protect synthesis and secretion of thyroid hormone by upregulating the expression levels of thyroid hormone synthesis-related proteins and promotingting Thyroid peroxidase (TPO) activity through S-sulphydration of sirtuin-1 (SIRT-1). Depending on this fact we measured the HS level in a group of hypothyroid patient. The plasma H S level in case in our study was 33.95 ± 4.14 micromol/l with the range from 27.82 to 43.94 micromol/l. This was significantly (P< 0>  

Keywords: Hypothyroidism, Thyroid

How to cite : Bhattacharya A, Banerjee S, Bhattacharyya I, Saha P, Sanyal D, Biswas I B, An observational study to determine relationship of serum hydrogen sulphide level in hypothyroid patients in a medical college in Kolkata. Panacea J Med Sci 2023;13(3):824-828

Copyright © 2023 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)