Panacea Journal of Medical Sciences

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Retrospective study of CNS tumors in a tertiary care centre in Western Odisha - A 4 year study

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Original Article

Author Details : Sobhagini Nayak, Kaustav Mohapatra, Jyotirmayee Mishra*, Harish Chandra Singh

Volume : 14, Issue : 1, Year : 2024

Article Page : 57-62

https://10.18231/j.pjms.2024.012

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Abstract

Background: Central nervous system (CNS) tumors comprise nearly 3% of all malignancies world-wide whereas in India it accounts for about 2%. In recent years there has been an increase in CNS tumors with new potential risk factors being observed.
Objective: The aim of the present study is to highlight the histopathological spectrum of brain tumors in a single tertiary care centre in Western Odisha.
Materials and Methods: This retrospective histopathological analysis of CNS tumors was conducted in the Department of Pathology, VIMSAR, Burla, Odisha, India from October 2016 to September 2020. In the span of 4 years, a total of 94 neurosurgical biopsies were studied. Histopathological examination of routinely processed tissue and hematoxylin and eosin (H&E) stained sections of corresponding cases were thoroughly examined. Immunohistochemistry (IHC) was done whenever required. Thereafter an approach was made to diagnose the cases, based on WHO classification system of 2016.
Results: A wide range of histopathological spectrum of CNS tumors was observed and was classified according to the WHO classification system of 2016. The primary CNS tumors were graded from Grade I to Grade IV. The most common CNS tumor in our study we found to be Astrocytic tumors (21 cases, 22.34%) followed by Schwannoma (19 cases, 20.21%) and meningiomas (18 cases, 19.14%). The incidence was more among males (59.51%) as compared to females (40.4%).
Conclusion: This study provides an information regarding the prevalence of disease in Western Odisha. Use of modern imaging technique helps to a major extent in making a provisional.
 
Keywords: Central nervous system tumors, Glioma, Meningioma, Histopathology, Immunohistochemistry

How to cite : Nayak S, Mohapatra K, Mishra J, Singh H C, Retrospective study of CNS tumors in a tertiary care centre in Western Odisha - A 4 year study. Panacea J Med Sci 2024;14(1):57-62

Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)