Panacea Journal of Medical Sciences

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Study the beneficial effects of oxygen blender during cardiopulmonary bypass in reducing lactate levels in patients undergoing open-heart surgery

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Original Article

Author Details : B Rajesh, B Karthikeyan*, A S Mughilan, P Anbukumar, Marwin Manoa Baylis

Volume : 14, Issue : 1, Year : 2024

Article Page : 82-87

https://10.18231/j.pjms.2024.016

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Abstract

Introduction: Serum lactate levels rise during Cardio-Pulmonary Bypass (CPB) surgery for a variety of reasons, including peripheral circulatory failure, haemodilution, or excessive use of inotropic agents. Additionally, it has been reported that elevated serum lactate levels during the perioperative period are strongly associated with the worst postoperative outcomes, including mortality.
Aim: To find out the beneficial effects of an oxygen blender during cardiopulmonary bypass in reducing lactate levels in patients undergoing open-heart surgery.
Materials and Methods: This Prospective comparative study was done on 150 patients who underwent open-heart surgeries. Patients were divided into group A-75 patients: with direct oxygen flow without oxygen blender, group B- 75 patients: with oxygen blender. The serum lactate levels during CPB, postoperative levels and outcomes were monitored and both the groups were compared.
Results: Average FIO2 of 38 % was enough to maintain PO2 of 168 mm Hg by using the oxygen blender with the flow rates. Group A showed severe hyperoxemia (p-value <0> Conclusion: Serum lactate values reduced significantly in the patients with oxygen blender. Study proved that application of an oxygen blender during CPB improved the postoperative results following open-heart surgeries. The researchers conclude that using an oxygen mask was beneficial.
 

Keywords: Hyperlactemia, Cardiopulmonary bypass, Oxygen blender, Hyperoxemia, Hypocarbia

How to cite : Rajesh B, Karthikeyan B, Mughilan A S, Anbukumar P, Baylis M M, Study the beneficial effects of oxygen blender during cardiopulmonary bypass in reducing lactate levels in patients undergoing open-heart surgery. Panacea J Med Sci 2024;14(1):82-87

Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)