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Panacea Journal of Medical Sciences


To study thyroid profile in CKD patients in Eastern Uttar Pradesh


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Original Article

Author Details : Anupam Srivastava*, Mahim Mittal, Minakshi Awasthi, Priyanka Rai, Mahima Goel

Volume : 14, Issue : 1, Year : 2024

Article Page : 283-287

https://10.18231/j.pjms.2024.050

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Abstract

Background: Chronic kidney disease (CKD) remains a universal pandemic that has evolved into a serious public health problem that imposes a significant socioeconomic burden. Thyroid profile is disrupted in CKD patients due to aberrant thyroid hormone metabolism. The purpose of our study was to assess thyroid function in people who had chronic renal disease (CKD).
Materials and Methods: According to the inclusion-exclusion criteria, this cross-sectional observational research enrolled 150 chronic renal disease patients.All patients who met the above criteria underwent a detailed history as well as a general and systemic examination. Thyroid function tests, USG entire abdomen, chest X-ray, ECG, and 2D Echocardiogram, were performed.
Results: There were 84 men and 66 women among the 150 CKD patients. Thyroid hormone abnormalities were found in 93.3 % of the individuals. 14.7 % of the participants had hypothyroidism, 14.7 % had low T3 and T4 readings, 10% had low T4 values alone, 38 % had low T3 only, and 17% had subclinical hypothyroidism. Low T3 levels (58 %) were the most prevalent thyroid anomaly, with or without low T4 or elevated TSH levels. Low T3 levels were more common in patients with advanced CKD.
Conclusion: Thyroid hormone abnormalities are linked to different stages of chronic renal disease.
 

Keywords: Chronic Kidney Disease, Hypothyroidism, Thyroid profile, Low T3, Thyroid hormone abnormalities


How to cite : Srivastava A, Mittal M, Awasthi M, Rai P, Goel M, To study thyroid profile in CKD patients in Eastern Uttar Pradesh. Panacea J Med Sci 2024;14(1):283-287

Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)