Panacea Journal of Medical Sciences
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Print ISSN:-2249-8176
Online ISSN:-2348-7682
CODEN : PJMSD7
Current Issue
Year 2024
Volume: 14 , Issue: 2
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Original Article
Author Details :
Volume : 14, Issue : 2, Year : 2024
Article Page : 332-336
https://10.18231/j.pjms.2024.058
Abstract
Objective: Purpose of this study is to evaluate prescribing pattern of NSAIDS in osteoarthritis patients and their effect on symptoms and disease progression
Materials and Methods: The Prospective observational study was performed on 200 study participants of both sexes from orthopaedic Out Patient Department (OPD) from a tertiary care hospital, Prakash Institute of medical science in Kolhapur between span of Aug 2019 to Aug 2020 who were diagnosed with Osteoarthritis and prescribed with NSAIDS for a minimum period of 3 months. After the period of treatment improvement in symptom was assessed by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scale to evaluate specific symptoms in subsequent visit at interval of 1 month for 3 follow ups.
Results: Most common NSAIDs prescribed in orthopaedic OPD patients were diclofenac (51%), Paracetamol (50.5%), Aceclofenac (43%), Tramadol (15%), Ibuprofen (7%), etoricoxib (6%), Naproxen (5%). Paracetamol was most frequently prescribed as combination therapy along with diclofenac, Tramadol and aceclofenac, and diclofenac was commonly used as monotherapy. Tramadol combined with paracetamol has been used in only 22 patients (13%) in the present study. Changes in pain, stiffness and physical function subscale after 3 months follow up were significant compare to initial visit in WOMAC score.
Conclusion: Non-steroidal anti-inflammatory drugs are most commonly used drug for the management of pain and inflammation. From our study it was observed that conventional type of NSAIDS are used most common. NSAIDs are vital for clinical management of OA and to improve quality of life. Aceclofenac with paracetamol combination therapy and Diclofenac monotherapy were most frequently prescribed among the NSAIDs. Safety is the proven concern in treating chronic conditions in OA, hence Aceclofenac and Paracetamol is recommended as combination therapy.
Keywords: Osteoarthritis, Non-steroidal anti-inflammatory drugs, Cyclooxygenase
How to cite : Byndoor Y, Sagar T V , Palla J , Agrawal D , Kumar S, Swain T R , Prescription pattern of non-steroidal anti-inflammatory drugs and their effects on symptoms and disease progression in patients with osteoarthritis in tertiary care centre. Panacea J Med Sci 2024;14(2):332-336
Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)
