Panacea Journal of Medical Sciences

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A study of thyroid profile in chronic liver disease patients attending a tertiary care center in Kumaon region of Uttarakhand

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Original Article

Author Details : Vivekanand Satyawali*, Seema Gupta, Yogesh Kumar, Devansh Satyawali

Volume : 14, Issue : 2, Year : 2024

Article Page : 345-349

https://10.18231/j.pjms.2024.061

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Abstract

Introduction: The liver is crucial for the metabolism of thyroid hormone and production of thyroxine-binding globulin production (TBG). Liver dysfunction can result from changes in thyroid function, and distinct liver conditions can have different impacts on the metabolism of thyroid hormones
Objectives: This study tries to find out the relationship between thyroid function and liver disease.
Materials and Methods: The cross-sectional, institution-based observational study from January 2020 to September 2021. The study population included patients with chronic liver disease who visited the OPD or were admitted to the medical wards of Dr. Susheela Tiwari memorial hospital, a tertiary care hospital of Kumaon region of Uttarakhand. The study proforma included the demographic data, history, clinical examination and details of investigations. Tests performed included Complete Hemogram, Liver function tests, Serum creatinine, Blood urea, Serum electrolytes, Abdominal ultrasound, Prothrombin time, INR and thyroid function tests.
Results: Mean serum T3 and T4 level didn’t follow any uniform trend with the severity of disease, however mean TSH increased with the increase in the severity of the disease. Although this was not found to be statistically significant.
Conclusion: The thyroid dysfunction holds an important place in the spectrum of Chronic liver disease. Progressive worsening of liver function increases likely hood of abnormal underlying thyroid dysfunction and therefore, patients need to be evaluated for thyroid dysfunction periodically.
 

Keywords: Correlation, chronic Liver Disease, Thyroid profile

How to cite : Satyawali V, Gupta S, Kumar Y, Satyawali D, A study of thyroid profile in chronic liver disease patients attending a tertiary care center in Kumaon region of Uttarakhand. Panacea J Med Sci 2024;14(2):345-349

Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)