Panacea Journal of Medical Sciences
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Print ISSN:-2249-8176
Online ISSN:-2348-7682
CODEN : PJMSD7
Current Issue
Year 2024
Volume: 14 , Issue: 2
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Original Article
Author Details :
Volume : 14, Issue : 2, Year : 2024
Article Page : 395-399
https://10.18231/j.pjms.2024.070
Abstract
Background: It has been noted in many studies that there are hormonal imbalances in critically ill patients. We have undertaken this study to clarify whether thyroid profile can independently predict mortality & disease severity in ICU patients and whether there is any correlation between the thyroid profile & SOFAS scores.
Materials and Methods: Current study was cross sectional in nature conducted on 152 critically ill sepsis patients. All patients fulfilling eligibility criteria of our study were included.
Results: There were 85 (55.92%) survivors & 67 (44.08%) non-survivors in the study. Mean age of the survivors was 58.33 + 12.56 years vs. 62.46 + 14.22 years among non-survivors. Mean FT3 level was significantly more reduced among non-survivors (1.5 ± 0.77 pmol/l) than the survivors (2.02 ± 0.66 pmol/l). Mean FT4 level though decreased, it did not differ between the two groups. While mean TSH level was significantly raised among non-survivors (5.23 ± 0.96 ?IU/l) than the survivors (4.92 ± 0.96 ?IU/l). Serum FT3 levels in both the groups were negatively correlated with disease severity i.e. duration of mechanical ventilation, duration of ICU stay & with SOFA scores.
Conclusion: FT3 can be used as a proxy indicator of SOFA scores for assessing disease severity & predicting prognosis of critically ill patients in ICU.
Keywords: SOFA score, FT3, Thyroid profile, critically ill, ICU patients
How to cite : Sanjay B, Neel C, Asim G, Shubham B, Abhijeet D, Assessment of thyroid profile in critically ill patients by using SOFA score in a tertiary care hospital. Panacea J Med Sci 2024;14(2):395-399
Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)
