Panacea Journal of Medical Sciences

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Unusual presentations of chronic osteomyelitis caused by unusual pathogens: A case series from a tertiary care hospital of eastern India

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Case Series

Author Details : Ananda Sanchayeeta Mandal, Deboprio Das, Hirak Jyoti Raj*

Volume : 14, Issue : 2, Year : 2024

Article Page : 593-601

https://10.18231/j.pjms.2024.106

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Abstract

Chronic osteomyelitis is multifactorial in its occurrence, type, severity and prognosis. Presentation of chronic osteomyelitis may be varied even very unlike of its prototype. Cases of osteomyelitis were encountered caused by Nocardia brasiliensis, Actinomyces spp., Aspergillus flavus, Staphylococcus aureus, Morganella morganii with unusual presentations. The organisms except Staphylococcus aureus were among the seldomly reported ones. Two of the cases were found to be biofilm associated as studied by biofilm detection throughatomic force microscopy and methods of Anderl et al and Stepanovic et al. Only one case,c aused by biofilm producer strain of No cardia brasiliensis, required surgical correction with amputation. Rest four cases were recovered with antimicrobial therapy. Strong degree of suspicion of biofilm development and involvement of unusual etiological agents were required to diagnose and treat the cases of chronicity. It could put aside the drastic decisions like amputation which might be associated with immense eco-socio-psychological impact onthe patients and their families.
 

Keywords: chronic osteomyelitis, unusual, pathogen

How to cite : Mandal A S, Das D, Raj H J, Unusual presentations of chronic osteomyelitis caused by unusual pathogens: A case series from a tertiary care hospital of eastern India. Panacea J Med Sci 2024;14(2):593-601

Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)