Panacea Journal of Medical Sciences
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Official Publication of NKP Salve Institute of Medical Sciences and Research Centre
Print ISSN:-2249-8176
Online ISSN:-2348-7682
CODEN : PJMSD7
Current Issue
Year 2024
Volume: 14 , Issue: 3
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Original Article
Author Details :
Volume : 14, Issue : 3, Year : 2024
Article Page : 724-728
https://10.18231/j.pjms.2024.129
Abstract
Background: The primary cause of coronary artery disease is atherosclerosis and its complications. Formation of coronary thrombus and initiation of atherosclerotic lesions are significantly influenced by platelets and their activity. Compared to smaller platelets, giant platelets have a larger potential thrombotic ability and are more metabolically and enzymatically active.
Aim: The objective of the current research is to determine the significance and role of platelet indices by comparing the values in patients with Acute Coronary Syndrome (ACS) to those in healthy controls.
Materials and Methods: This prospective case-control study was carried out in a tertiary care centre with 100 cases and 100 controls for 6 months. Blood samples were taken when the patient was admitted. Platelet indices were measured within 30 minutes of blood collection using an automated haematology analyzer.
Results: Platelet indices such as Mean platelet volume, Platelet distribution width and Platelet large cell ratio were substantially greater in patients with ACS than in healthy controls. Platelet count and Plateletcrit showed lower level in ACS patients with respect to controls.
Conclusion: Platelet indices measurement would be beneficial in estimating those patients at greater risk for developing ACS in the future.
Keywords: Platelet indices, Coronary artery disease, Acute coronary syndrome
How to cite : Koppalkar R, Athira K P, Amber S, Significance of impedance based platelet parameters in prediction of acute coronary syndromes. Panacea J Med Sci 2024;14(3):724-728
Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)
