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Year 2024

Volume: 14 , Issue: 3

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Panacea Journal of Medical Sciences


Chronic myeloid leukemia in lymphoid blast crisis with extramedullary CNS infiltration in a pediatric patient: A case report


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Case Report

Author Details : Mintu Ann Joy, Vandana Bhatti, Ravneet Singh Heer*, Kripa M Mathews

Volume : 14, Issue : 3, Year : 2024

Article Page : 886-888

https://10.18231/j.pjms.2024.157

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Abstract

Chronic Myeloid Leukemia (CML) is a myeloproliferative disorder, characterized by BCR-ABL1 fusion resulting from t(9;22)(q34;q11) translocation. It constitutes 2% of all leukemia cases in children younger than 15 years. CML-Blast crisis (CML-BC) with extramedullary CNS involvement is a rare serious complication of CML with a poor prognosis.Lymphoid BC in CML is seen in 30% of cases.We present a case of an 8-year-old girl diagnosed with CML one year prior to presentation, who now presented with lymphoid BC with central nervous system (CNS) involvement.
 

Keywords: Acute lymphoblastic leukemia, Central nervous system, Chronic myeloid leukemia, CML, Lymphoid blast crisis, Paediatric


How to cite : Joy M A, Bhatti V, Heer R S, Mathews K M, Chronic myeloid leukemia in lymphoid blast crisis with extramedullary CNS infiltration in a pediatric patient: A case report. Panacea J Med Sci 2024;14(3):886-888

Copyright © 2024 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)