Panacea Journal of Medical Sciences

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Metastatic breast carcinoma involving the thyroid gland: A rare case report and literature review

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Author Details : Litake MM, Moger J, Parasnis A

Volume : 5, Issue : 2, Year : 2015

Article Page : 92-95

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Abstract

Being a rare site of metastasis, breast carcinoma metastasis to thyroid is rare. Presenting herewith a case of carcinoma breast operated one year ago in a 65 year old woman with negative for ER/PR and HER-2-neu status. She presented a year later after postoperative chemo-radiotherapy to our hospital with thyroid swellings and cervical lymphadenopathy. PET scan revealed spinal metastasis in thoracolumbar segments and suspicious thyroid malignancy. Ultrasonography of the neck was suspicious of thyroid neoplasia. Histo-pathological examination of total thyroidectomy revealed metastatic invasive ductal carcinoma of breast and immunohistochemistry was positive for GCDFP-15 and negative for thyroglobulin and TTF-1.

Keywords: GCDFP-15 (Gross cystic disease fluid protein-15), TTF-1 (Thyroid transcription factor-1), Breast carcinoma.

How to cite : Litake Mm, Moger J, Parasnis A, Metastatic breast carcinoma involving the thyroid gland: A rare case report and literature review. Panacea J Med Sci 2015;5(2):92-95

Copyright © 2015 by author(s) and Panacea J Med Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)