Pattern of antimicrobial sensitivity in Enterococcus in case of urinary tract infection, 5 years experiences in a tertiary care hospital
Article Type : Original Article
Author Details:
Volume : 9
Issue : 3
Online ISSN : 2348-7682
Print ISSN : 2249-8176
Article First Page : 88
Article End Page : 91
Abstract
Introduction: Urinary tract infection is very common in our community mostly in females and enterococcal infection is very frequent. There is gradual development of resistance against this organism thus narrowing the spectrum of susceptibility.
Aims: So, the aim of this study to detect the spectrum of sensitivity pattern in case of enterococcus in case of urinary tract infection.
Materials and Methods: In this retrospective cross sectional study, morning midstream clean-catch urine form total 1550 symptomatic patients was studied for the spectrum of antibiotic susceptibility according to Clinical & laboratory Standard Institute (CLSI) guideline.
Results: Total 189 patients were infected with enterococci. They showed sensitivity to Vancomycin (87.83%), Teicoplanin (85.18%), Lenazolid (84.12%) and nitrofurantoin (74.07%), and moderate degree of sensitivity in piperacillin-tazobactam (67.19%), imipenem (64.60%) and gentamicin (46.56%) and Amoxycillin-clavulanic acid (54.49%).
Conclusion: Proper antibiotic-stewardship is ultimate requirement to prevent the development of bacterial resistance. So, regular surveillance as well as monitoring is very much necessary to update the knowledge about the susceptibility pattern of urinary pathogens which will guide the therapy.
Keyword: Enterococcus, Symptomatic urinary tract infections, Culture and sensitivity, Tertiary medical centre.
Doi No:-10.18231/j.pjms.2019.022