Panacea Journal of Medical Sciences

A study of the correlation between mean platelet volume and diabetic retinopathy in patients with type 2 diabetes mellitus

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Article Type : Original Article

Author Details: Yeruva Poulina Deepthi Reddy,S Vithiavathi*,G Kalaiselvi

Volume : 10

Issue : 1

Online ISSN : 2348-7682

Print ISSN : 2249-8176

Article First Page : 10

Article End Page : 12

Abstract

Diabetic retinopathy (DR), a kind of micro vascular lesion that is detected on fundus examination, accounts for 40 percent of diabetics over 40 years of age. To determine the correlation of mean platelet volume with diabetic retinopathy.
Methodology: Hospital based Case- Control study. 50 patients diagnosed as Type-2 diabetes mellitus with defined diabetic retinopathy. And 50 patients with age and sex matched without the case disease. To all the patients mean platelet volume was done and comparing the significant difference of mean platelet volume between diabetics with retinopathy (cases) and control groups.
Results: The mean platelet volume of the diabetic retinopathy and controls were 11.77 + 1.40 and 7.55 + 0.35. Regarding fasting glucose level for diabetic retinopathy and controls were 196.04 + 13.2 and 103.57+12.16 which is significantly higher than the controls (p value <0>+ 1.01 which is significantly higher than the control groups 5.48+0.94. (p value <0>
Conclusion: Mean platelet volume was reported to be raised in diabetic retinopathy patients compared to the healthy population.

Keywords: Diabetic Retinopathy, Mean Platelet Volume, HbA1c, Diabetes Mellitus

Doi No:-10.18231/j.pjms.2020.003