Santosh University Journal of Health Sciences

Efficacy and safety of intravenous iron sucrose versus oral iron in pregnant women with mild to moderate iron deficiency anaemia

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Article Type : Original Article

Author Details: Neelima Agarwal, Amita Sharma, Manisha Gupta, Alpana Agrawal

Volume : 2

Issue : 2

Online ISSN : 2455-1732

Print ISSN :

Article First Page : 109

Article End Page : 111

Abstract

Background: Efficient treatment of iron deficiency anaemia in pregnant women would lead to a considerable reduction in the risk factors, affecting maternal and fetal outcome.
Patients and Methods: This prospective study was carried out in 84 women between 20 to 34 weeks of pregnancy with established iron deficiency anaemia and haemoglobin 6-10g/dL. They were randomised to receive either oral or intravenous iron in required dose. Haemoglobin and ferritin levels were measured at recruitment and after 4 weeks of therapy. Adverse drug reactions were also noted in both the groups. Results were analysed by student’s t-test.
Results:  The mean increase in haemoglobin values with IV sucrose group was 1.26 ±0.58g % as compared to 0.78 ±0.37 gm% in oral iron group after 4 weeks of oral iron therapy (p<0.03). Similarly, The mean increase in ferritin values with IV sucrose group was 12.00 ± 11.77ng/ml  as compared to 6.50 ± 9.53ng/ml  in oral iron group (p<0.02).
Conclusion: This study indicates iron sucrose not only treats but also corrects iron stores which are not seen with oral iron.

Keywords: Iron deficiency anaemia, Iron sucrose, Oral iron therapy

Doi No:-10.18231