Santosh University Journal of Health Sciences

Comparison of systemic autonomic functions in primary angle glaucoma and in normal subjects

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Article Type : Original Article

Author Details: Mohammad Monis Khan, Varun Malhotra, Yogesh Tripathi, Usha Dhar, Shivani Gupta

Volume : 2

Issue : 2

Online ISSN : 2455-1732

Print ISSN :

Article First Page : 117

Article End Page : 121

Abstract

The present study was conducted to assess the autonomic activity in 30 normal healthy [control] and 30 Primary Open Angle Glaucoma [POAG] subjects. The studies related to record the autonomic dysfunction in POAG was undertaken. The results showed that both the parameters used for sympathetic as well as parasympathetic activities were found to be statistically highly significant except in the case of resting heart rate. No changes were observed in the normal subjects. The changes in the parameters of autonomic function [i.e. Resting HR, T-wave amplitude, QTc, S/L ratio, Valsalva ratio and Cold Pressor Response] in the present study helped concluding that the autonomic involvement in POAG is present. POAG showed decrease in both the sympathetic and parasympathetic activity. Early detection and treatment of risk factors e.g. cardiovascular factors [systemic hypertension, hypotension], sympathetic and parasympathetic dysfunctions that affect optical circulation, aqueous production and innervations of ciliary body, muscles and processes is essential before irreversible changes set in and effect vision.

Keywords: POAG Primary Open Angle Glaucoma, Autonomic Function

Doi No:-10.18231