Telangana Journal of Psychiatry

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Neuropsychiatric manifestations associated with systemic lupus erythematosus: A case report and selective review of literature

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Case Report

Author Details : Udayan Bhaumik, Hemendra Singh*

Volume : 4, Issue : 2, Year : 2018

Article Page : 106-108

https://10.18231/2455-8559.2018.0013

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Abstract

Introduction: Systemic lupus erythematosus (SLE) is an autoimmune condition affecting multiple organ systems including central nervous system. Its aetiology lies in abnormal antibody formation and complement activation. Neuropsychiatric manifestations are known to occur in patients with SLE, and vary from psychosis, depression, anxiety to cognitive impairment. Here we report a case of depression with psychotic symptoms and suicidal ideations associated with SLE.
Case Summary: We present the case of a 30-year-old female who presented with irritability, crying spells, feeling of guilt, referential and persecutory ideations along with suicidal ideations. She was diagnosed with severe depression with psychotic symptoms associated with SLE. She improved over a period of 6 weeks with Quetiapine 300mg along with symptomatic management of underlying medical condition.
Conclusions: Depression with psychotic symptoms is not an uncommon presentation of SLE. It needs comprehensive management and multidisciplinary approach. Hence physician has to be sensitized regarding neuropsychiatric manifestations of SLE for improving the morbidity and mortality associated with underlying depression.

Keywords: SLE-Depression-Psychosis.

How to cite : Bhaumik U, Singh H, Neuropsychiatric manifestations associated with systemic lupus erythematosus: A case report and selective review of literature. Telangana J Psychiatry 2018;4(2):106-108

Copyright © 2018 by author(s) and Telangana J Psychiatry. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International License (creativecommons.org)