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Journal of International College of Dentists

Journal of International College of Dentists (JICD) is an open-access, peer-reviewed, Quarterly journal publishing under the auspices of the International College of Dentists. As soon as the Article is accepted for Publication, it will be placed in “Ahead of Print” on the journal page with the aim of rapid and better knowledge dissemination. In addition, the journal allows free access (Open Access) to its contents, which is likely to attract more readers and citations to articles published in journal. Manuscripts must be prepared under the “Uniform r...

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COMPARATIVE ANALYSIS OF CLINICAL FINDING AND HISTOPATHOLOGICAL DIAGNOSIS FOR LEUKOPLAKIA 

  • Author Details:   
  • Rajbir Kaur Khangura,  
  • Neeraj Grover,  
  • Shamindra Sengupta,  
  • Dilpreet Singh Grewal,  
  • Karan Rajpal,  
  • Aanchal Puri
Page: 69-70

BACKGROUND: The potentially malignant oral lesions (PMOL) demand that the final diagnosis should be made on both clinical as well as histopathologic examination. The aim of the present study was to determine the correlation between clinical and histopathologic diagnosis of leukoplakia using a discrepancy index (DI) and evaluate clinical as well as histological variations seen in leukoplakia in our department over 8 year(2004-2012) time period.

METHODS: The study consisted of 196 cases clinically examined and diagnosed as leukoplakia. The results of histopathologic diagnosis were compared with the clinical diagnosis. The histopathologic diagnosis was incompatible when the clinical diagnosis was not confirmed histologically. On the basis of the incompatible diagnosis, we calculated a discrepancy index between the clinical and histopathologic diagnosis.

RESULTS: Out of 196 cases clinically diagnosed as leukoplakia, 157 cases (80.10%) were histologically also diagnosed as showing features of dysplasia whereas 39 cases were diagnosed as some other lesion. The discrepancy between clinical and histological diagnosis of leukoplakia was 19.89%.

CONCLUSION: In 80.10% of leukoplakias the clinical diagnosiswas confirmed by histopathologic examination. The discrepancy between the clinicaland histopathologic diagnoses in 19.89% of cases suggests that all leukoplakia should be submitted to a histopathologic analysis as there are chances of missing out early oral squamous cell carcinoma or carcinoma in situ.

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