Santosh University Journal of Health Sciences

Association of body mass index with serum 25 hydroxy Vitamin D status in healthy pre and postmenopausal females

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Article Type : Original Article

Author Details: Jyoti Batra,Sudeep Kumar*,Manisha Arora,Sumesh Prasad Sah,Roshan Kumar Mahat

Volume : 4

Issue : 2

Online ISSN : 2455-1732

Print ISSN :

Article First Page : 82

Article End Page : 86

Abstract

Introduction: BMI is associated with Vitamin D in pre and postmenopausal women. As the estrogen level decreases during menopause, this promotes hypovitaminosis D. The present study assessed Vitamin D status and found its correlation with BMI in healthy pre- and postmenopausal women.
Materials and Methods: This cross-sectional study was conducted on 100 pre-menopausal and 100 postmenopausal women. Blood samples were collected for estimation of Vitamin D by fully automated Chemi Luminescent Immuno Assay. Statistical analyses were done by using Graphpad Prism 6 and Pearson correlation coefficient was computed between Vitamin D and BMI.
Results: The mean levels of weight and BMI were increased significantly in post-menopausal women as compared to premenopausal women and the mean level of Vitamin D was decreased significantly in postmenopausal women as compared to premenopausal. In the present study, we observed that the BMI is significantly and negatively correlated with Vitamin D concentration in both pre (r=-0.549) and postmenopausal (r=-0.736) women and it was statistically significant.
Conclusion: Vitamin D deficiency is prevalent in pre- and postmenopausal with BMI greater than 25 kg/meter² and the decrease in Vitamin D was more in postmenopausal women as compared to premenopausal women and the Vitamin D was negatively associated with BMI in both pre and postmenopausal women.

Keywords: Postmenopausal, BMI, Vitamin D, Estrogen, Osteoporosis

Doi No:-10.18231/2455-1732.2018.0019